ST6GAL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15907.
生物活性 | Testing in progress |
产品描述 | ST6GAL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15907. |
种属 | Human |
表达系统 | HEK293 |
标签 | His |
蛋白编号 | P15907 |
别名 | ST6 β-galactosamide α-2,6-sialyltranferase 1, ST6 beta-galactosamide alpha-2,6-sialyltranferase 1, SIAT1, ST6 beta-galactosamide α-2,6-sialyltranferase 1, ST6GalI, ST6N |
蛋白构建 | A DNA sequence encoding the human ST6GAL1 (P15907) (Lys 27-Cys 406) was expressed, with a polyhistidine tag at the N-terminus. |
蛋白纯度 | ≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. |
分子量 | 46 kDa (predicted) |
内毒素 | < 1.0 EU per μg of the protein as determined by the LAL method |
缓冲液 | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type II membrane protein that belongs to the glycosyltransferase 29 family. Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an oligosaccharidic acceptor. ST6GAL1 / SIAT1 is normally found in the Golgi but can be proteolytically processed to a soluble form. It is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. β-Galactoside α2,6-sialyltransferases ST6GAL1 and ST6GAL2 are the two unique members of the ST6GAL family described in higher vertebrates. ST6GAL1 / SIAT1 transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. |
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ST6GAL1 Protein, Human, Recombinant (His) SIAT 1 ST6 β-galactosamide α-2,6-sialyltranferase 1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 SIAT1 ST6 beta-galactosamide α-2,6-sialyltranferase 1 ST6GalI SIAT-1 ST6 b-galactosamide a-2,6-sialyltranferase 1 ST6N recombinant recombinant-proteins proteins protein