The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,700 | 5日内发货 | ||
500 μg | ¥ 14,800 | 5日内发货 | ||
1 mg | ¥ 24,700 | 5日内发货 |
生物活性 | Immobilized SARS-COV-2 Spike S Trimer, His Tag at 1μg/ml (100μl/Well). Dose response curve for Human ACE2, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA. |
产品描述 | The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
种属 | SARS-CoV-2 |
表达系统 | HEK293 |
标签 | C-His-Avi |
蛋白编号 | A0A6G7K2L4 |
别名 | COVID-19, S protein, S glycoprotein, Spike glycoprotein |
蛋白构建 | Recombinant SARS-COV-2 Spike S is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Val16-Glu1188.[Accession |QHD43416.1] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | The protein has a predicted MW of 136.6 kDa. Due to glycosylation, the protein migrates to 175-230 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
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SARS-COV-2 Spike S Trimer Protein (His & Avi) COVID19 COVID-19 S protein COVID 19 S glycoprotein Spike glycoprotein recombinant recombinant-proteins proteins protein