Siglec-3/CD33 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.6 kDa and the accession number is P20138-1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 5,180 | 5日内发货 | ||
500 μg | ¥ 20,700 | 5日内发货 | ||
1 mg | ¥ 34,600 | 5日内发货 |
生物活性 | Immobilized Biotinylated Human Siglec-3, His Tag at 0.5μg/ml (100μl/Well) on streptavidin (5μg/ml) precoated plate. Dose response curve for Anti-Siglec-3 Antibody, hFc Tag with the EC50 of 4.4ng/ml determined by ELISA. |
产品描述 | Siglec-3/CD33 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.6 kDa and the accession number is P20138-1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-His-Avi |
蛋白编号 | P20138-1 |
别名 | Siglec3, p67, FLJ00391, Siglec-3, gp67, CD33, CD33 molecule |
蛋白构建 | Asp18-His259 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC |
分子量 | 29.6 kDa (predicted). Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result. |
内毒素 | < 1 EU/μg by the LAL method. |
缓冲液 | Supplied as 0.22 μm filtered solution in 50m MES, 500 mM NaCl, 200 mM L-arginine (pH 7.4). |
存储 |
It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. |
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Siglec-3/CD33 Protein, Human, Recombinant (His & Avi), Biotinylated CD-33 FLJ 00391 Siglec3 p67 FLJ00391 CD 33 Siglec-3 gp67 CD33 FLJ-00391 CD33 molecule recombinant recombinant-proteins proteins protein