Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 220 | 5日内发货 | ||
50 μg | ¥ 540 | 5日内发货 | ||
500 μg | ¥ 1,930 | 5日内发货 | ||
1 mg | ¥ 2,760 | 5日内发货 |
产品描述 | Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins. |
种属 | Human |
表达系统 | E. coli |
标签 | N-6His |
蛋白编号 | Q96LD8 |
别名 | DEN1, Protease Cysteine 2, NEDP1, Sentrin-Specific Protease 8, Deneddylase-1, PRSC2, SENP8, NEDD8-Specific Protease 1, Sentrin/SUMO-Specific Protease SENP8 |
氨基酸序列 | Met1-Lys212 |
蛋白构建 | Recombinant Human Sentrin-Specific Protease 8 is produced by our E.coli expression system and the target gene encoding Met1-Lys212 is expressed with a 6His tag at the N-terminus. |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 22 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
存储 |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
运输方式 |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins. |
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SENP8 Protein, Human, Recombinant (His) NEDP 1 DEN1 Protease Cysteine 2 NEDP1 SENP-8 Sentrin-Specific Protease 8 Deneddylase-1 PRSC2 PRSC-2 SENP8 DEN-1 SENP 8 DEN 1 PRSC 2 NEDP-1 NEDD8-Specific Protease 1 Sentrin/SUMO-Specific Protease SENP8 recombinant recombinant-proteins proteins protein