SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 220 | 5日内发货 | ||
50 μg | ¥ 700 | 5日内发货 | ||
500 μg | ¥ 4,740 | 5日内发货 | ||
1 mg | ¥ 7,510 | 5日内发货 |
产品描述 | SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. |
种属 | Human |
表达系统 | E. coli |
标签 | N-6His,SUMO |
蛋白编号 | Q9HC62 |
别名 | Sentrin/SUMO-specific protease SENP2, Axam2, SMT3-specific isopeptidase 2, SENP2., Sentrin-specific protease 2, KIAA1331 |
氨基酸序列 | Asp363-Leu589 |
蛋白构建 | Recombinant Human Sentrin-specific Protease 2 is produced by our E.coli expression system and the target gene encoding Asp363-Leu589 is expressed. |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 29 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of 50mM HEPES, 5% Glycerol, pH 7.4. |
存储 |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
运输方式 |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. |
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SENP2 Protein, Human, Recombinant Sentrin/SUMO-specific protease SENP2 KIAA 1331 KIAA-1331 Axam2 SMT3-specific isopeptidase 2 SENP2. Sentrin-specific protease 2 KIAA1331 recombinant recombinant-proteins proteins protein