S100A13 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.6 kDa and the accession number is Q99584.
生物活性 | Testing in progress |
产品描述 | S100A13 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.6 kDa and the accession number is Q99584. |
种属 | Human |
表达系统 | E. coli |
标签 | Tag Free |
蛋白编号 | Q99584 |
别名 | protein S100-A13, OTTHUMP00000034802, S100 calcium-binding protein A13, S100 calcium binding protein A13 |
蛋白构建 | A DNA sequence encoding the native human S100A13 (NP_001019381.1) (Met 1-Lys 98) was expressed. |
蛋白纯度 | > 98 % as determined by SDS-PAGE |
分子量 | 11.6 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Lyophilized from sterile 20mM Tris, 100mM NaCl, pH 8.0. Pleasecon tact usfor any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A13, also known as S100 calciumbinding protein A13, is a member of the S-100 family. It contains two EF-hand domains. S100A13 binds two calcium ions per subunit and one copper ion. Binding of one copper ion does not interfere with calcium-binding. S100A13 is required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine. S100A13 plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. |
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S100A13 Protein, Human, Recombinant OTTHUMP-00000034802 protein S100-A13 OTTHUMP00000034802 OTTHUMP 00000034802 S100 calcium-binding protein A13 S100 calcium binding protein A13 recombinant recombinant-proteins proteins protein