Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 could be a potential tumor-associated antigen for mammary cancer immunological prevention. Up to now, the experimental evidence uncovering the role of RCN2 in cancer is very limited.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 820 | 5日内发货 | ||
50 μg | ¥ 2,480 | 5日内发货 | ||
500 μg | ¥ 12,100 | 5日内发货 | ||
1 mg | ¥ 17,400 | 5日内发货 |
产品描述 | Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 could be a potential tumor-associated antigen for mammary cancer immunological prevention. Up to now, the experimental evidence uncovering the role of RCN2 in cancer is very limited. |
种属 | Human |
表达系统 | Human Cells |
标签 | C-6His |
蛋白编号 | Q14257 |
别名 | Reticulocalbin-2, ERC55, RCN2, E6BP |
氨基酸序列 | Gly23-Leu317 |
蛋白构建 | Recombinant Human Reticulocalbin-2 is produced by our Mammalian expression system and the target gene encoding Gly23-Leu317 is expressed with a 6His tag at the C-terminus. |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 50-55 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, 1mM DTT, pH 8.0. |
存储 |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
运输方式 |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 could be a potential tumor-associated antigen for mammary cancer immunological prevention. Up to now, the experimental evidence uncovering the role of RCN2 in cancer is very limited. |
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RCN2 Protein, Human, Recombinant (His) Reticulocalbin-2 ERC-55 RCN-2 ERC 55 ERC55 RCN2 E6BP RCN 2 recombinant recombinant-proteins proteins protein