PVRIG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is A0A2K5WVV8.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 550 | 5日内发货 | ||
50 μg | ¥ 1,670 | 5日内发货 | ||
500 μg | ¥ 14,200 | 5日内发货 | ||
1 mg | ¥ 21,300 | 5日内发货 |
产品描述 | PVRIG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is A0A2K5WVV8. |
种属 | Cynomolgus |
表达系统 | HEK293 Cells |
标签 | C-6xHis |
蛋白编号 | A0A2K5WVV8 |
别名 | CD112R, C7orf15MGC138295, MGC104322, transmembrane protein PVRIG, MGC138297, PVRIG, C7orf15, MGC2463 |
氨基酸序列 | Thr41-Asp171 |
蛋白构建 | Thr41-Asp171 |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 20-30 KDa (reducing condition) |
内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The extracellular domain sequence of human and mouse PVRIG have approximately 65% similarity. PVRIG functions as a cell surface receptor for Nectin-2/CD112, a cell surface protein that is widely expressed on antigen-presenting cells and tumor cells. Disrupting the PVRIG/Nectin-2 interaction enhances human T cell response, suggesting PVRIG is a novel checkpoint for human T cells. PVRIG may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. |
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PVRIG Protein, Cynomolgus, Recombinant (His) MGC-2463 CD112R MGC 2463 C7orf15MGC138295 MGC104322 MGC 138297 transmembrane protein PVRIG MGC-138297 MGC138297 PVRIG MGC-104322 MGC 104322 C7orf15MGC-138295 C7orf15 MGC2463 C7orf15MGC 138295 recombinant recombinant-proteins proteins protein