PTX3 Protein, Mouse, Recombinant (His)

Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.

规格	价格/CNY		数量
10 μg	￥ 1,170	5日内发货
50 μg	￥ 3,470	5日内发货
500 μg	￥ 12,100	5日内发货
1 mg	￥ 18,900	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,170

5日内发货

50 μg

￥ 3,470

5日内发货

500 μg

￥ 12,100

5日内发货

1 mg

￥ 18,900

5日内发货

产品描述

种属	Mouse
表达系统	Human Cells
标签	N-6His
蛋白编号	P48759
别名	alpha-induced protein 5, pentraxin 3, long, pentaxin-related gene, rapidly induced by IL-1 β, tumor necrosis factor, Pentaxin-related protein PTX3, pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, pentraxin-related gene, rapidly induced by IL-1 beta, Pentraxin 3, pentraxin-3, pentraxin-related gene, rapidly induced by IL-1 β, pentraxin-related protei, α-induced protein 5
氨基酸序列	Glu18-Ser381
蛋白构建	Recombinant Mouse Pentraxin-related protein PTX3 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser381 is expressed with a 6His tag at the N-terminus.
蛋白纯度	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量	54 KDa, reducing conditions

内毒素	Less than 1 EU/µg as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
存储	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输方式	The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
研究背景	Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.

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PTX3 Protein, Mouse, Recombinant (His)

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