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OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)

OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPJ-01441
别名: OX-40L, TNFSF4, Tumor necrosis factor ligand 2B

Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.

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OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 550 5日内发货
50 μg ¥ 1,670 5日内发货
500 μg ¥ 13,700 5日内发货
1 mg ¥ 20,500 5日内发货
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产品目录号及名称: OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His) (TMPJ-01441)
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生物活性
技术参数
产品性质
生物活性 Immobilized Human OX40-Fc at 10μg/ml (100 μl/well)can bind Cynomolgus OX40L-His. The ED50 of Cynomolgus OX40L-Hisis 17.75 ng/ml. (Regularly tested)
产品描述 Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.
种属 Cynomolgus
表达系统 Human Cells
标签 N-8His
蛋白编号 F7FL80
别名 OX-40L, TNFSF4, Tumor necrosis factor ligand 2B
氨基酸序列 Gln51-Leu183
蛋白构建 Recombinant Cynomolgus OX40 Ligand is produced by our Mammalian expression system and the target gene encoding Gln51-Leu183 is expressed with a 8His tag at the N-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 23-30 Kda, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶方法 Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
存储

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

运输方式

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

研究背景 Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.

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Keywords

OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His) OX-40L TNFSF 4 TNFSF-4 TNFSF4 Tumor necrosis factor ligand 2B recombinant recombinant-proteins proteins protein

 

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