NLGN4X Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.9 kDa and the accession number is A0A024RBV0.
生物活性 | Testing in progress |
产品描述 | NLGN4X Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.9 kDa and the accession number is A0A024RBV0. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-His |
蛋白编号 | A0A024RBV0 |
别名 | HLNX, neuroligin 4, X-linked, AUTSX2, ASPGX2, NLGN4, KIAA1260, HNL4X |
蛋白构建 | The Human NLGN4X (NP_065793.1) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus. |
蛋白纯度 | > 95 % as determined by SDS-PAGE. |
分子量 | 72.9 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | NLGN4X (Neuroligin 4 X-Linked) is a Protein Coding gene. This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. NLGN4X interacts with discs large homolog 4 (DLG4). It is broadly expressed in the brain, ovary, and other tissues. Genetic mutations in NLGN4X, including point mutations and copy number variants (CNVs), have been associated with susceptibility to autism spectrum disorders (ASDs). Pathogenic mutations in the NLGN4X gene in ASDs and/or mental retardation (MR) are rare. Based on in vitro models, NLGN4X knockdown directly impacts the neurodevelopmental process during the formation of neurons and their connections. |
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NLGN4X Protein, Human, Recombinant (His) HLNX neuroligin 4, X-linked ASPGX 2 NLGN 4 KIAA 1260 AUTSX2 ASPGX2 NLGN4 AUTSX 2 KIAA-1260 NLGN-4 AUTSX-2 KIAA1260 ASPGX-2 HNL4X recombinant recombinant-proteins proteins protein