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NLGN4X Protein, Human, Recombinant (hFc)

NLGN4X Protein, Human, Recombinant (hFc)

产品编号 TMPY-00562
别名: neuroligin 4, X-linked, AUTSX2, HNL4X, KIAA1260, NLGN4, HLNX, ASPGX2

NLGN4X Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 98.2 kDa and the accession number is A0A024RBV0.

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NLGN4X Protein, Human, Recombinant (hFc)
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 5日内发货
药物设计专题培训
千万补贴 助力科研
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产品目录号及名称: NLGN4X Protein, Human, Recombinant (hFc) (TMPY-00562)
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生物活性 Testing in progress
产品描述 NLGN4X Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 98.2 kDa and the accession number is A0A024RBV0.
种属 Human
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 A0A024RBV0
别名 neuroligin 4, X-linked, AUTSX2, HNL4X, KIAA1260, NLGN4, HLNX, ASPGX2
蛋白构建 The Human NLGN4X (NP_065793.1) (Met1-Ser676) was expressed with the Fc region of Human IgG1 at the C-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 98.2 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 NLGN4X (Neuroligin 4 X-Linked) is a Protein Coding gene. This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. NLGN4X interacts with discs large homolog 4 (DLG4). It is broadly expressed in the brain, ovary, and other tissues. Genetic mutations in NLGN4X, including point mutations and copy number variants (CNVs), have been associated with susceptibility to autism spectrum disorders (ASDs). Pathogenic mutations in the NLGN4X gene in ASDs and/or mental retardation (MR) are rare. Based on in vitro models, NLGN4X knockdown directly impacts the neurodevelopmental process during the formation of neurons and their connections.

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Keywords

NLGN4X Protein, Human, Recombinant (hFc) NLGN 4 KIAA-1260 neuroligin 4, X-linked AUTSX2 HNL4X AUTSX 2 ASPGX 2 NLGN-4 KIAA1260 AUTSX-2 NLGN4 ASPGX-2 HLNX KIAA 1260 ASPGX2 recombinant recombinant-proteins proteins protein

 

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