Mucin-17/MUC17 Protein, Human, Recombinant (His)

Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression of MYH9 and p53, and activates the p38 pathway in GC cells through RhoA signalling.

规格	价格/CNY		数量
10 μg	￥ 550	5日内发货
50 μg	￥ 1,670	5日内发货
500 μg	￥ 15,400	5日内发货
1 mg	￥ 23,100	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 550

5日内发货

50 μg

￥ 1,670

5日内发货

500 μg

￥ 15,400

5日内发货

1 mg

￥ 23,100

5日内发货

产品描述

种属	Human
表达系统	Human Cells
标签	C-6His
蛋白编号	Q685J3
别名	Mucin-17, MUC-17, MUC17, MUC3, MUC-3
氨基酸序列	Arg4131-Leu4390
蛋白构建	Recombinant Human Mucin-17 is produced by our Mammalian expression system and the target gene encoding Arg4131-Leu4390 is expressed with a 6His tag at the C-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	45-55&25-30&17-21 kDa, reducing conditions

内毒素	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression of MYH9 and p53, and activates the p38 pathway in GC cells through RhoA signalling.

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Mucin-17/MUC17 Protein, Human, Recombinant (His)

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