Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury.
生物活性 | The specific activity was determined to be >30 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate. |
产品描述 | Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury. |
种属 | Human |
表达系统 | Baculovirus-Insect Cells |
标签 | His |
蛋白编号 | Q9Y6E0-2 |
别名 | HEL-S-95, STE20, MST3B, RP11-111L24.5, MST3, STK3, serine/threonine kinase 24 |
蛋白构建 | A DNA sequence encoding the human STK24 isoform A (Q9Y6E0-2) (Met 1-His 431) was expressed, with a polyhistidine tag at the N-terminus. |
蛋白纯度 | > 82 % as determined by SDS-PAGE |
分子量 | Approxiamtely 50.3 kDa |
内毒素 | < 1.0 EU per μg of the protein as determined by the LAL method |
缓冲液 | Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.0, 20% gly, 0. 1mM EGTA, 0. 1mM EDTA, 0. 25mM DTTPlease contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products. |
研究背景 | Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury. |
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MST3 Protein, Human, Recombinant (His) HEL-S-95 STE20 MST3B RP11-111L24.5 STE 20 MST 3 STK-3 MST3 STE-20 MST-3 STK 3 STK3 serine/threonine kinase 24 recombinant recombinant-proteins proteins protein