LRRC15 Protein, Human, Recombinant (hFc)

LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmembrane protein demonstrated to play important roles in cancer. LRRC15 is highly expressed in multiple solid tumor indications with limited normal tissue expression. It was expressed on stromal fibroblasts in many solid tumors (e.g., breast, head, and neck, lung, pancreatic) as well as directly on a subset of cancer cells of mesenchymal origin (e.g., sarcoma, melanoma, glioblastoma). The tumor antigen LRRC15, which is frequently overexpressed in multiple tumor types, as a repressor of cell death due to adenoviral p53.

规格	价格/CNY		数量
100 μg	￥ 3,300	现货
200 μg	￥ 5,830	5日内发货
500 μg	￥ 12,350	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 3,300

现货

200 μg

￥ 5,830

5日内发货

500 μg

￥ 12,350

5日内发货

生物活性

Immobilized Recombinant Human LRRC15 Protein (ECD, Fc Tag) at 2 μg/mL (100 μL/well) can bind Anti-LRRC15 Antibody（Samrotamab）, the EC50 is 6.5-20 ng/mL.

TargetMol Bioactive

产品描述

种属	Human
表达系统	HEK293
标签	hFc
蛋白编号	Q8TF66-1
别名	leucine rich repeat containing 15, LIB
蛋白构建	A DNA sequence encoding the human LRRC15 (NP_570843.2) (Met1-Gly538) was expressed with the Fc region of human IgG1 at the C-terminus.
蛋白纯度	> 85 % as determined by SDS-PAGE.
分子量	Approxiamtely 84.5 kDa

内毒素	< 1.0 EU per μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法	A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmembrane protein demonstrated to play important roles in cancer. LRRC15 is highly expressed in multiple solid tumor indications with limited normal tissue expression. It was expressed on stromal fibroblasts in many solid tumors (e.g., breast, head, and neck, lung, pancreatic) as well as directly on a subset of cancer cells of mesenchymal origin (e.g., sarcoma, melanoma, glioblastoma). The tumor antigen LRRC15, which is frequently overexpressed in multiple tumor types, as a repressor of cell death due to adenoviral p53.

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LRRC15 Protein, Human, Recombinant (hFc)

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