Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated

Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF-beta RI or ALK-1, to modulate transcription through Smad phosphorylation.

规格	价格/CNY		货期	数量
20 μg	￥ 5,730	5日内发货
100 μg	￥ 15,800	5日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 5,730

5日内发货

100 μg

￥ 15,800

5日内发货

产品描述

种属	Human
表达系统	Human Cells
标签	N-8His-Avi
蛋白编号	P10600
别名	Transforming growth factor β-3, Latent TGF-β3, TGF-β-3, TGFβ3, TGFB3, TGF-beta-3, Transforming growth factor beta-3 proprotein, 转化生长因子
氨基酸序列	Leu30-Ser390
蛋白构建	Biotinylated Recombinant Human Transforming Growth Factor Beta-3 Proprotein is produced by our Mammalian expression system and the target gene encoding Leu30-Ser390 (Cys33Ser) is expressed with a 8His, Avi tag at the N-terminus.
蛋白纯度	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量	12&37-45 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF-beta RI or ALK-1, to modulate transcription through Smad phosphorylation.

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Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated

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