L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 2,660 | 现货 | ||
500 μg | ¥ 10,600 | 5日内发货 | ||
1 mg | ¥ 17,800 | 5日内发货 |
产品描述 | L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers. |
种属 | Mouse |
表达系统 | HEK293 |
标签 | C-His |
蛋白编号 | P11627 |
别名 | CALL, MGC132578, FLJ44930, NCAM-L1, MIC5, CHL-1, SPG1, HSAS, CD171, L1CAM, N-CAM-L1, CAML1, S10, L1CAM-2, CHL1, MASA, HSAS1 |
蛋白构建 | Recombinant Mouse L1CAM Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ile20-Glu1123.[Accession |P11627] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 125.4 kDa. Due to glycosylation, the protein migrates to 160-180 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per ug by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers. |
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L1CAM Protein, Mouse, Recombinant (His) CALL MGC132578 FLJ44930 CAML-1 CD-171 NCAM-L1 MIC5 S 10 CD 171 CHL-1 SPG1 HSAS SPG 1 MGC-132578 CD171 CHL 1 SPG-1 L1CAM MIC 5 MGC 132578 HSAS 1 S-10 FLJ 44930 N-CAM-L1 CAML1 S10 CAML 1 L1CAM-2 CHL1 FLJ-44930 MIC-5 HSAS-1 MASA HSAS1 recombinant recombinant-proteins proteins protein