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Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)

Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)

产品编号 TMPJ-00475
别名: Tissue Kallikrein, Kidney/Pancreas/Salivary Gland Kallikrein, Kallikrein-1, KLK1

Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.

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Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His) (TMPJ-00475)
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产品性质
产品描述 Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.
种属 Human
表达系统 Human Cells
标签 C-6His
蛋白编号 AAH05313.1
别名 Tissue Kallikrein, Kidney/Pancreas/Salivary Gland Kallikrein, Kallikrein-1, KLK1
氨基酸序列 Pro19-Ser262
蛋白构建 Recombinant Human Kallikrein 1 is produced by our Mammalian expression system and the target gene encoding Pro19-Ser262 is expressed with a 6His tag at the C-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 38-55 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl<sub>2</sub>, pH 8.0.
存储

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

运输方式

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

研究背景 Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.

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Keywords

Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His) KLK 1 Tissue Kallikrein KLK-1 Kidney/Pancreas/Salivary Gland Kallikrein Kallikrein-1 KLK1 recombinant recombinant-proteins proteins protein

 

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