FGF-7/KGF Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 21 kDa and the accession number is P36363.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 μg | ¥ 2,940 | 5日内发货 | ||
1 mg | ¥ 21,700 | 5日内发货 |
生物活性 | 1.Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human FGFR2b. The ED50 for this effect is typically 20-100 ng/mL. 2.Mouse Bladder Organoids after 14 days in culture.25 ng/mL of Recombinant Mouse KGF/FGF-7 Protein (50394-M07E) was used for 2 weeks in BME submerged in mouse bladder media.Data provided by Dr. Yin at Washington University, St. Louis, MO. |
产品描述 | FGF-7/KGF Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 21 kDa and the accession number is P36363. |
种属 | Mouse |
表达系统 | E. coli |
标签 | His |
蛋白编号 | P36363 |
别名 | Kgf, fibroblast growth factor 7, 成纤维细胞生长因子 |
蛋白构建 | A DNA sequence encoding the mouse FGF7 (NP_032034.1) (Cys32-Thr194) was expressed with a polyhistidine tag at the N-terminus. |
蛋白纯度 | > 90 % as determined by SDS-PAGE |
分子量 | 21 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Lyophilized from sterile 10 mM Na2HPO4, 1. 8 mM KH2PO4, 2. 7 mM KCl, 140 mM NaCl, 15 % glycerol. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Fibroblast growth factor 7 (FGF7) is a member of the fibroblast growth factor (FGF) family of proteins. FGF7 plays an important role in regulating the proliferation, migration, and differentiation of cells. FGF7 is of stromal origin and produces a paracrine effect on epithelial cells. FGF7 is a mesenchyme-specific heparin-binding growth factor that binds FGF receptor 2 (FGFR2) to regulate numerous cellular and physiological processes. FGF7/FGFR2 promotes invasion and migration in human gastric cancer. FGF7 is specifically utilized as a paracrine factor during the process of differentiation of the epidermal layers in the regenerating scales and in particular for beta-cells differentiation. FGF7 over expression is associated with advanced clinical features in patients with upper tract and bladder urothelial carcinoma, justifying its potential prognostic value for urothelial carcinoma. |
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FGF-7/KGF Protein, Mouse, Recombinant (His) Kgf fibroblast growth factor 7 成纤维细胞生长因子 recombinant recombinant-proteins proteins protein