Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 1,170 | 现货 | ||
50 μg | ¥ 3,470 | 5日内发货 | ||
500 μg | ¥ 16,100 | 5日内发货 | ||
1 mg | ¥ 24,100 | 5日内发货 |
产品描述 | Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses. |
种属 | Human |
表达系统 | Human Cells |
标签 | C-Fc |
蛋白编号 | P01583 |
别名 | Hematopoietin-1, Interleukin-1 Alpha, 白介素, IL-1 α, IL1A, 白细胞介素, IL1F1, Interleukin-1 α, IL-1 Alpha |
氨基酸序列 | Ser113-Ala271 |
蛋白构建 | Recombinant Human Interleukin-1 alpha is produced by our Mammalian expression system and the target gene encoding Ser113-Ala271 is expressed with a human IgG1 Fc tag at the C-terminus. |
蛋白纯度 |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
|
分子量 | 54 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5. |
复溶方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
存储 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
运输方式 |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses. |
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IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) Hematopoietin-1 Interleukin-1 Alpha 白介素 IL-1 α IL1A 白细胞介素 IL1F1 Interleukin-1 α IL-1 Alpha recombinant recombinant-proteins proteins protein