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IL-18RAP Protein, Human, Recombinant (hFc & His)

IL-18RAP Protein, Human, Recombinant (hFc & His)

产品编号 TMPJ-00344
别名: IL-1R accessory protein-like, Interleukin-18 receptor β, C, IL18RAP, CD218 antigen-like family member B, Interleukin-1 receptor 7, Accessory protein-like, Interleukin-18 receptor accessory protein, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, CDw218b

IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

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IL-18RAP Protein, Human, Recombinant (hFc & His)
规格 价格/CNY 货期 数量
10 μg ¥ 380 5日内发货
50 μg ¥ 1,170 5日内发货
500 μg ¥ 8,600 5日内发货
1 mg ¥ 12,800 5日内发货
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产品目录号及名称: IL-18RAP Protein, Human, Recombinant (hFc & His) (TMPJ-00344)
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产品描述 IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
种属 Human
表达系统 Human Cells
标签 C-Fc-6His
蛋白编号 O95256
别名 IL-1R accessory protein-like, Interleukin-18 receptor β, C, IL18RAP, CD218 antigen-like family member B, Interleukin-1 receptor 7, Accessory protein-like, Interleukin-18 receptor accessory protein, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, CDw218b
氨基酸序列 Phe20-Arg356
蛋白构建 Recombinant Human Interleukin-18 receptor accessory protein is produced by our Mammalian expression system and the target gene encoding Phe20-Arg356 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 88 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶方法 Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
存储

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

运输方式

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

研究背景 IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

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Keywords

IL-18RAP Protein, Human, Recombinant (hFc & His) IL-1R accessory protein-like Interleukin-18 receptor β C IL18RAP CD218 antigen-like family member B Interleukin-1 receptor 7 Accessory protein-like Interleukin-18 receptor accessory protein Interleukin-18 receptor accessory protein-like Interleukin-18 receptor beta CDw218b recombinant recombinant-proteins proteins protein

 

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