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IL-17F Protein, Human, Recombinant (His)

IL-17F Protein, Human, Recombinant (His)

产品编号 TMPJ-00573
别名: IL17F, IL-17F, Cytokine ML-1, Interleukin-17F

IL-17F Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession number is AAH70124.1.

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IL-17F Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 820 5日内发货
50 μg ¥ 2,480 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: IL-17F Protein, Human, Recombinant (His) (TMPJ-00573)
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生物活性
技术参数
产品性质
生物活性 1. Loaded Biotinylated Human IL-17RA-His-Avi on SA Biosensor, can bind Human IL-17F -His with an affinity constant of 81.3 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Mouse IL-17RA-Fc at 1μg/ml (100 μl/well)can bind Human IL-17F-His. The ED50 of Human IL-17F-His is 47.94 ng/ml. (Regularly tested)
产品描述 IL-17F Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession number is AAH70124.1.
种属 Human
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 AAH70124.1
别名 IL17F, IL-17F, Cytokine ML-1, Interleukin-17F
氨基酸序列 Arg31-Gln163
蛋白构建 Arg31-Gln163
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 19 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).

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Keywords

IL-17F Protein, Human, Recombinant (His) IL17F IL-17F Cytokine ML-1 Interleukin-17F recombinant recombinant-proteins proteins protein

 

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