IL-17F Protein, Human, Recombinant

Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.

规格	价格/CNY		数量
10 μg	￥ 910	5日内发货
50 μg	￥ 2,760	5日内发货
500 μg	￥ 12,100	5日内发货
1 mg	￥ 17,400	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 910

5日内发货

50 μg

￥ 2,760

5日内发货

500 μg

￥ 12,100

5日内发货

1 mg

￥ 17,400

5日内发货

生物活性

1. Loaded Biotinylated Human IL-17RA-His-Avi on HIS1K Biosensor, can bind Human IL-17F with an affinity constant of 0.56 uM nM as determined in BLI assay. (Regularly tested) 2. Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 5-40 ng/ml. (QC verified) 3. Immobilized Human IL-17F at 2μg/ml (100 μl/well)can bind Biotinylated Human IL-17RA-His-Avi. The ED50 of Biotinylated Human IL-17RA-His-Avi is 0.11 ug/ml. (Regularly tested)

产品描述

种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	Q96PD4
别名	IL17F, 白介素, IL-17F, Interleukin-17F, 白细胞介素, Cytokine ML-1
氨基酸序列	Arg31-Gln163
蛋白构建	Arg31-Gln163
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	15 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.

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Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

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IL-17F Protein, Human, Recombinant

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技术支持

Keywords