IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.

规格	价格/CNY		数量
10 μg	￥ 380	现货
20 μg	￥ 610	5日内发货
50 μg	￥ 1,170	5日内发货
100 μg	￥ 1,700	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 380

现货

20 μg

￥ 610

5日内发货

50 μg

￥ 1,170

5日内发货

100 μg

￥ 1,700

5日内发货

生物活性

1. Loaded Human IL-2RA-Fc on Protein A Biosensor, can bind Human IL-2 Superkine with an affinity constant of 10.4 nM as determined in BLI assay. (Regularly tested) 2. Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 151.39 pg/ml. (Regularly tested)

TargetMol Bioactive

产品描述

种属	Human
表达系统	Human Cells
标签	C-6His
蛋白编号	P60568
别名	TCGF, Aldesleukin, T-Cell Growth Factor, IL-2, Interleukin-2, IL2
氨基酸序列	Ala21-Thr153
蛋白构建	Recombinant Human Interleukin-2 Superkine is produced by our Mammalian expression system and the target gene encoding Ala21-Thr153 (L100F, R101D, L105V, I106V, I112F) is expressed with a 6His tag at the C-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.

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比活力计算器

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Mass (in vial)

Desired Reconstitution Concentration

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IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

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