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IgG2a Protein, Rat, Recombinant

IgG2a Protein, Rat, Recombinant

产品编号 TMPJ-00893
别名: Ig γ-2A chain C region, Ig gamma-2A chain C region, Igg-2a

Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

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IgG2a Protein, Rat, Recombinant
规格 价格/CNY 货期 数量
10 μg ¥ 220 5日内发货
50 μg ¥ 700 5日内发货
500 μg ¥ 4,740 5日内发货
1 mg ¥ 7,510 5日内发货
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产品目录号及名称: IgG2a Protein, Rat, Recombinant (TMPJ-00893)
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产品性质
产品描述 Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.
种属 Rat
表达系统 HEK293 Cells
标签 Tag Free
蛋白编号 P20760
别名 Ig γ-2A chain C region, Ig gamma-2A chain C region, Igg-2a
氨基酸序列 Val98-Lys322
蛋白构建 Val98-Lys322
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 30-35 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, pH 8.5.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

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Keywords

IgG2a Protein, Rat, Recombinant Ig γ-2A chain C region Ig gamma-2A chain C region Igg-2a recombinant recombinant-proteins proteins protein

 

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