IFNGR1 Protein, Rat, Recombinant (hFc)

IFNGR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q6P6T3.

规格	价格/CNY		货期	数量
100 μg	￥ 2,530	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 2,530

5日内发货

生物活性

1. Measured by its binding ability in a functional ELISA. Immobilized Rat IFNGR1 hFc at 2 μg/ml (100 μl/well) can bind Rat Interferon Gamma hFc, Biotinylated the EC50 of Rat Interferon Gamma hFc, Biotinylated is 60-300 ng/mL. 2. Measured by its ability to inhibit rat IFNγ-mediated protection of L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is typically 0.5-4 ng/mL in the presence of 10 ng/mL of recombinant rat IFN-gamma.

产品描述

IFNGR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q6P6T3.

种属	Rat
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q6P6T3
别名	interferon gamma receptor 1, interferon γ receptor 1
蛋白构建	The Rat IFNGR (Q6P6T3) (Met1-Ser241) was expressed with the Fc region of Human IgG1 at the C-terminus.
蛋白纯度	> 95 % as determined by SDS-PAGE
分子量	52.4 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon-gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interferon receptor while the IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types.