Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,100 | 5日内发货 | ||
500 μg | ¥ 12,400 | 5日内发货 | ||
1 mg | ¥ 20,700 | 5日内发货 |
生物活性 | Cynomolgus IFN alpha/beta R2, His Tag captured on CM5 Chip via anti-his antibody can bind Human IFN alpha 1, hFc Tag with an affinity constant of 70.28 nM as determined in SPR assay. |
产品描述 | Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. |
种属 | Cynomolgus |
表达系统 | HEK293 |
标签 | C-His |
蛋白编号 | G7P6B3 |
别名 | β receptor10, IFNbR2, IFN α/β R2, IFN-R, IFNAR2, β receptor 2, IFN-α/β R2, IFN-α, IFN-alpha, IFN-alpha/beta R2, IFN-R-2, IFNARB, IFNABR |
蛋白构建 | Recombinant Cynomolgus IFN alpha/beta R2 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ile27-Lys243.[Accession |EHH53981.1] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 25.93 kDa. Due to glycosylation, the protein migrates to 43-60 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) β receptor10 IFNbR2 IFN-a/b R2 b receptor10 IFN α/β R2 IFN-R IFNAR2 b receptor 2 β receptor 2 IFN-α/β R2 IFNAR 2 IFN-α IFN-alpha IFN-alpha/beta R2 IFN-R-2 beta receptor 2 IFNARB IFNABR beta receptor10 IFNAR-2 recombinant recombinant-proteins proteins protein