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HSPB8 Protein, Human, Recombinant (His)

HSPB8 Protein, Human, Recombinant (His)

产品编号 TMPJ-01382
别名: Small stress protein-like protein HSP22, CRYAC, E2IG1, Alpha-crystallin C chain, α-crystallin C chain, HspB8, Heat shock protein β-8, Protein kinase H11, HSP22, E2-induced gene 1 protein, Heat shock protein beta-8

Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

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HSPB8 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: HSPB8 Protein, Human, Recombinant (His) (TMPJ-01382)
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产品描述 Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
种属 Human
表达系统 E. coli
标签 C-6His
蛋白编号 Q9UJY1
别名 Small stress protein-like protein HSP22, CRYAC, E2IG1, Alpha-crystallin C chain, α-crystallin C chain, HspB8, Heat shock protein β-8, Protein kinase H11, HSP22, E2-induced gene 1 protein, Heat shock protein beta-8
氨基酸序列 Met1-Thr196
蛋白构建 Recombinant Human Heat Shock Protein Beta-8 is produced by our E.coli expression system and the target gene encoding Met1-Thr196 is expressed with a 6His tag at the C-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 23 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, pH 7.4.
存储

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

运输方式

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

研究背景 Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

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Keywords

HSPB8 Protein, Human, Recombinant (His) Small stress protein-like protein HSP22 CRYAC a-crystallin C chain E2IG1 Alpha-crystallin C chain α-crystallin C chain HspB8 Heat shock protein β-8 Protein kinase H11 HSP 22 Heat shock protein b-8 HSP22 E2-induced gene 1 protein HSP-22 Heat shock protein beta-8 recombinant recombinant-proteins proteins protein

 

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