NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 926 | 待询 | ||
1 mg | ¥ 6,227 | 待询 |
生物活性 | Immobilized Anti-HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Antibody at 5μg/ml (100μl/well) on the plate. Dose response curve for Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer, His Tag with the EC50 of 7.2ng/ml determined by ELISA. |
产品描述 | NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. |
种属 | Human |
表达系统 | E. coli |
标签 | C-His-Avi |
蛋白编号 | A0A140T913(HLA-A*02:01)&P61769(B2M)&SLLMWITQC |
别名 | MHC, CT6.1, CTAG1, LAGE-2, MY-ESO-1, NY-ESO-1, ESO1CTAG, LAGE2A, CTAG1B |
蛋白构建 | Recombinant Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus. It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and SLLMWITQC peptide.[Accession |A0A140T913(HLA-A*02:01)&P61769(B2M)&SLLMWITQC] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Supplied as 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). |
存储 |
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. |
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HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi) MHC CT6.1 CTAG1 LAGE-2 MY-ESO-1 NY-ESO-1 ESO1CTAG LAGE2A CTAG1B recombinant recombinant-proteins proteins protein