Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,250 | 5日内发货 | ||
500 μg | ¥ 13,000 | 5日内发货 | ||
1 mg | ¥ 21,700 | 5日内发货 |
产品描述 | Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. |
种属 | Canine |
表达系统 | HEK293 |
标签 | C-His |
蛋白编号 | F1PAG3 |
别名 | GC-C, GUCY2C, STAR, EC 4.6.1, STA receptor, GCC, MUCIL, Guanylyl cyclase C, GUC2CEC 4.6.1.2, GUC2C, DIAR6 |
蛋白构建 | Recombinant Canine GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Tyr21-Gln430.[Accession |F1PAG3] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 47.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per ug by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. |
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GUCY2C Protein, Canine, Recombinant (aa 21-430, His) GC-C GUCY2C STAR EC 4.6.1 DIAR 6 STA receptor GCC MUCIL DIAR-6 Guanylyl cyclase C GUC2CEC 4.6.1.2 GUC2C DIAR6 recombinant recombinant-proteins proteins protein