GPRC5D Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 5,330 | 5日内发货 | ||
100 μg | ¥ 10,600 | 5日内发货 | ||
500 μg | ¥ 33,800 | 5日内发货 |
生物活性 | Immobilized Biotinylated Human GPRC5D-VLP (Full Length) Protein at 5 μg/mL (100 μL/well) on streptavidin precoated (2 μg/well) can bind Anti-Human GPRC5D Antibody, Human IgG1, the EC50 is 4-12ng/mL. |
产品描述 | GPRC5D Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1. |
种属 | Human |
表达系统 | HEK293 |
标签 | Tag Free |
蛋白编号 | Q9NZD1-1 |
别名 | GPRC5D |
蛋白构建 | A DNA sequence encoding the human GPRC5D (Q9NZD1-1) (Met1-Val345) was expressed. |
分子量 | 38.80 kDa (predicted) |
内毒素 | < 1.0 EU per μg of the protein as determined by the LAL method |
缓冲液 | Supplied as sterile solution in 50mM HEPES, 150mM NaCI, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA. |
存储 |
Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
It is supplied and shipped as Solution with dry ice. |
研究背景 | Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells. |
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GPRC5D Protein, Human, Recombinant, Biotinylated GPRC5D recombinant recombinant-proteins proteins protein