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GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)

GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)

产品编号 TMPJ-00356
别名: GHBP, GHR, Somatotropin receptor, growth hormone receptor, growth hormone binding protein, GH receptor, serum binding protein

Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

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GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)
规格 价格/CNY 货期 数量
10 μg ¥ 580 5日内发货
50 μg ¥ 1,410 5日内发货
500 μg ¥ 9,960 5日内发货
1 mg ¥ 14,200 5日内发货
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产品目录号及名称: GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) (TMPJ-00356)
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产品性质
产品描述 Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.
种属 Mouse
表达系统 Human Cells
标签 C-Fc
蛋白编号 Q3UP14
别名 GHBP, GHR, Somatotropin receptor, growth hormone receptor, growth hormone binding protein, GH receptor, serum binding protein
氨基酸序列 Met1-Gln273
蛋白构建 Recombinant Mouse Growth Hormone Receptor is produced by our Mammalian expression system and the target gene encoding Met1-Gln273 is expressed with a human IgG1 Fc tag at the C-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 65-90 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶方法 Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
存储

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

运输方式

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

研究背景 Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

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Keywords

GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) GHBP GHR Somatotropin receptor growth hormone receptor growth hormone binding protein GH receptor serum binding protein recombinant recombinant-proteins proteins protein

 

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