Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,100 | 5日内发货 | ||
500 μg | ¥ 12,400 | 5日内发货 | ||
1 mg | ¥ 20,700 | 5日内发货 |
生物活性 | 1. Immobilized Cynomolgus GAS6, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Gas6 Antibody, hFc Tag with the EC50 of 26.1ng/ml determined by ELISA (QC Test). 2. Cynomolgus Axl, His Tag immobilized on CM5 Chip can bind Cynomolgus GAS6, His Tag with an affinity constant of 1.70 nM as determined in SPR assay. |
产品描述 | Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM). |
种属 | Cynomolgus |
表达系统 | HEK293 |
标签 | C-His |
蛋白编号 | A0A2K5VGX7 |
别名 | FLJ34709, AXLLG, GAS6, DKFZp666G247, GAS-6 |
蛋白构建 | Recombinant Cynomolgus GAS6 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ala31-Ala637.[Accession |A0A2K5VGX7] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 68.55 kDa. Due to glycosylation, the protein migrates to 69-74 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM). |
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GAS6 Protein, Cynomolgus, Recombinant (His) FLJ34709 DKFZp666G-247 AXLLG FLJ 34709 DKFZp666G 247 GAS 6 FLJ-34709 GAS6 DKFZp666G247 GAS-6 recombinant recombinant-proteins proteins protein