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FLT3 Ligand Protein, Human, Recombinant (His)

FLT3 Ligand Protein, Human, Recombinant (His)

产品编号 TMPY-03215
别名: fms related tyrosine kinase 3 ligand, FLT3L, FLT3LG, FL

FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.

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FLT3 Ligand Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,050 现货
20 μg ¥ 1,370 5日内发货
50 μg ¥ 1,950 5日内发货
100 μg ¥ 3,430 5日内发货
200 μg ¥ 6,070 5日内发货
500 μg ¥ 12,850 5日内发货
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产品目录号及名称: FLT3 Ligand Protein, Human, Recombinant (His) (TMPY-03215)
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生物活性
技术参数
产品性质
参考文献
生物活性 Measured in a cell proliferation assay using BaF3 mouse pro­B cells transfected with mouse Flt­3. The ED50 for this effect is typically 2-11 ng/mL.

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产品描述 FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.
种属 Human
表达系统 Baculovirus-Insect Cells
标签 His
蛋白编号 P49771-1
别名 fms related tyrosine kinase 3 ligand, FLT3L, FLT3LG, FL
蛋白构建 A DNA sequence encoding the human FLT3LG (P49771-1) (Thr27-Pro185) was expressed, with a polyhistidine tag at the N-terminus.
蛋白纯度 ≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

TargetMol TargetMol

分子量 20.2 kDa (predicted)
内毒素 < 1.0 EU per μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from sterile 20mM Tris, 300mM NaCl,10% glycerol, pH 7.5. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法 A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.

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Keywords

FLT3 Ligand Protein, Human, Recombinant (His) fms related tyrosine kinase 3 ligand FLT3L FLT3LG FL recombinant recombinant-proteins proteins protein

 

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