FKBP25/FKBP3 Protein, Human, Recombinant (His)

FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

规格	价格/CNY		数量
10 μg	￥ 380	5日内发货
50 μg	￥ 820	5日内发货
500 μg	￥ 5,130	5日内发货
1 mg	￥ 8,300	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 380

5日内发货

50 μg

￥ 820

5日内发货

500 μg

￥ 5,130

5日内发货

1 mg

￥ 8,300

5日内发货

产品描述

种属	Human
表达系统	E. coli
标签	N-6His
蛋白编号	Q00688
别名	25 kDa FKBP, FKBP-3, Peptidyl-prolyl cis-trans isomerase FKBP3, FKBP25, FKBP-25, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, PPIase FKBP3, 25 kDa FK506-binding protein, FK506-binding protein 3, Rotamase
氨基酸序列	Met1-Asp224
蛋白构建	Recombinant Human 25 kDa FK506-binding Protein is produced by our E.coli expression system and the target gene encoding Met1-Asp224 is expressed with a 6His tag at the N-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	30 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 10% Glycerol, pH 8.0.
存储	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输方式	The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
研究背景	FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

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FKBP25/FKBP3 Protein, Human, Recombinant (His)

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