FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,700 | 5日内发货 | ||
500 μg | ¥ 14,800 | 5日内发货 | ||
1 mg | ¥ 24,700 | 5日内发货 |
生物活性 | Immobilized Human FcRH5, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 21.1ng/ml determined by ELISA. |
产品描述 | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
种属 | Human |
表达系统 | HEK293 |
标签 | C-His |
蛋白编号 | AAK93971 |
别名 | FcR-like protein 5, CD307, BXMAS1, FcRH5, IFGP5, CD307e, FcRL5 |
蛋白构建 | Recombinant Human FcRH5/FcRL5 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gln16-Gly851.[Accession |AAK93971] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 92.38 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
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FcRH5/FcRL5 Protein, Human, Recombinant (His) FcR-like protein 5 CD307 IFGP-5 BXMAS1 BXMAS-1 CD-307 CD 307 BXMAS 1 FcRH5 IFGP5 IFGP 5 CD307e FcRL5 recombinant recombinant-proteins proteins protein