Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)

Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.

规格	价格/CNY		数量
100 μg	￥ 1,990	5日内发货
500 μg	￥ 8,000	5日内发货
1 mg	￥ 13,300	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 1,990

5日内发货

500 μg

￥ 8,000

5日内发货

1 mg

￥ 13,300

5日内发货

生物活性

Immobilized Human Fc epsilon RI alpha, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Fc epsilon RI alpha Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.

产品描述

种属	Human
表达系统	HEK293
标签	C-His
蛋白编号	P12319-1
别名	Fc-ε RI-α, Fc-epsilon RI-alpha, FCER1A, Fc-epsilon RI-α, FCE1A, FcERI, Fc epsilon RI α/FCER1a, Fc ε RI α/FCER1a
蛋白构建	Recombinant Human Fc epsilon RI alpha/FCER1a Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Val26-Gln205.[Accession \|P12319-1]
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	The protein has a predicted MW of 22.1 kDa. Due to glycosylation, the protein migrates to 48-65 kDa based on Tris-Bis PAGE result.

内毒素	Less than 1EU per ug by the LAL method.
缓冲液	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
存储	-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.