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FBPase1 Protein, Human, Recombinant (His, E. coli)

FBPase1 Protein, Human, Recombinant (His, E. coli)

产品编号 TMPJ-00815
别名: 6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP, FBPase 1, D-Fructose-1, 6-Bisphosphatase 1, Fructose-1

Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

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FBPase1 Protein, Human, Recombinant (His, E. coli)
规格 价格/CNY 货期 数量
10 μg ¥ 620 5日内发货
50 μg ¥ 1,730 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: FBPase1 Protein, Human, Recombinant (His, E. coli) (TMPJ-00815)
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产品描述 Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
种属 Human
表达系统 E. coli
标签 C-6xHis
蛋白编号 P09467
别名 6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP, FBPase 1, D-Fructose-1, 6-Bisphosphatase 1, Fructose-1
氨基酸序列 Ala2-Gln338
蛋白构建 Ala2-Gln338
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 38 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, 1 mM DTT, 1 mM EDTA, 20% Glycerol, pH 8.0.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

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Keywords

FBPase1 Protein, Human, Recombinant (His, E. coli) 6-Bisphosphate 1-Phosphohydrolase 1 FBP 1 FBP1 FBP FBPase 1 D-Fructose-1 FBP-1 6-Bisphosphatase 1 Fructose-1 recombinant recombinant-proteins proteins protein

 

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