The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 8,900 | 5日内发货 | ||
500 μg | ¥ 23,700 | 5日内发货 | ||
1 mg | ¥ 39,500 | 5日内发货 |
产品描述 | The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. |
种属 | Human |
表达系统 | HEK293 |
标签 | C-His-Avi |
蛋白编号 | P00533-1 |
别名 | EC 2.7.10.1, HER1, EGFR, PIG61, LEGFR, ErbB, ERBB1, mENA, EC 2.7.10, NISBD2 |
蛋白构建 | Recombinant FITC-Labeled Human EGFR/HER1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Leu25-Ser645.[Accession |P00533-1] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | The protein has a predicted MW of 71.5 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per ug by the LAL method. |
缓冲液 | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
存储 |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. |
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EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled EC 2.7.10.1 HER1 EGFR PIG61 NISBD-2 HER 1 LEGFR ERBB 1 PIG 61 ErbB ERBB1 ERBB-1 mENA HER-1 EC 2.7.10 PIG-61 NISBD2 NISBD 2 recombinant recombinant-proteins proteins protein