首页 工具
登录
购物车
Dtk Protein, Human, Recombinant (His)

Dtk Protein, Human, Recombinant (His)

产品编号 TMPJ-01081
别名: RSE, SKY, DTK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase receptor TYRO3, BYK, Tyrosine-protein kinase TIF, Tyrosine-protein kinase BYK, TIF, Tyrosine-protein kinase SKY, TYRO3

Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. The binding affinities for Gas6 is in the order of Axl < Dtk < Mer. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Dtk is widely expressed during embryonic development. In adults, Dtk is predominantly expressed in neurons in restricted regions of the brain.

TargetMol的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。
TargetMol
Dtk Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 540 5日内发货
50 μg ¥ 1,170 5日内发货
500 μg ¥ 5,250 5日内发货
1 mg ¥ 7,510 5日内发货
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
重组蛋白限时优惠
产品目录号及名称: Dtk Protein, Human, Recombinant (His) (TMPJ-01081)
点击图片重新获取验证码
更多批次查询请联系客服
生物活性
技术参数
产品性质
生物活性 Immobilized Human Dtk-His at 10μg/ml (100 μl/well) can bind Human GAS6-Fc. The ED50 of Human GAS6-Fc is 0.336 ug/ml. (Regularly tested)
产品描述 Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. The binding affinities for Gas6 is in the order of Axl > Dtk > Mer. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Dtk is widely expressed during embryonic development. In adults, Dtk is predominantly expressed in neurons in restricted regions of the brain.
种属 Human
表达系统 Human Cells
标签 C-6His
蛋白编号 Q06418
别名 RSE, SKY, DTK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase receptor TYRO3, BYK, Tyrosine-protein kinase TIF, Tyrosine-protein kinase BYK, TIF, Tyrosine-protein kinase SKY, TYRO3
氨基酸序列 Ala41-Ser428
蛋白构建 Recombinant Human Tyrosine-protein Kinase Receptor TYRO3 is produced by our Mammalian expression system and the target gene encoding Ala41-Ser428 is expressed with a 6His tag at the C-terminus.
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量 55-70 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶方法 Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
存储

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

运输方式

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

研究背景 Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. The binding affinities for Gas6 is in the order of Axl > Dtk > Mer. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Dtk is widely expressed during embryonic development. In adults, Dtk is predominantly expressed in neurons in restricted regions of the brain.

TargetMol Protein Calculator计算器

复溶计算器
重组蛋白稀释计算器
比活力计算器
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

技术支持

您可能有的问题的答案可以在重组蛋白操作手册中找到

Keywords

Dtk Protein, Human, Recombinant (His) RSE SKY DTK TYRO 3 TYRO-3 Tyrosine-protein kinase DTK Tyrosine-protein kinase RSE Tyrosine-protein kinase receptor TYRO3 BYK Tyrosine-protein kinase TIF Tyrosine-protein kinase BYK TIF Tyrosine-protein kinase SKY TYRO3 recombinant recombinant-proteins proteins protein

 

TargetMol Loading
陶术
生物
TargetMol®中国区唯一合作伙伴
点击进入陶术生物官网陶术生物
联系我们
400-820-0310

上海市静安区江场三路238号8楼