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DPYS Protein, Human, Recombinant (His & GST)

DPYS Protein, Human, Recombinant (His & GST)

产品编号 TMPY-03790
别名: DHPase, dihydropyrimidinase, DHP

DPYS Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 84.4 kDa and the accession number is Q14117.

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DPYS Protein, Human, Recombinant (His & GST)
规格 价格/CNY 货期 数量
100 μg ¥ 4,460 5日内发货
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
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产品目录号及名称: DPYS Protein, Human, Recombinant (His & GST) (TMPY-03790)
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产品描述 DPYS Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 84.4 kDa and the accession number is Q14117.
种属 Human
表达系统 Baculovirus-Insect Cells
标签 His,GST
蛋白编号 Q14117
别名 DHPase, dihydropyrimidinase, DHP
蛋白构建 A DNA sequence encoding the human DPYS (NP_001376.1) (Met1-Pro519) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 84.4 kDa (predicted)
内毒素 < 1.0 EU per μg of the protein as determined by the LAL method
缓冲液 Lyophilized from sterile 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 8.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法 A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 DPYS, also known as dihydropyrimidinase, belongs to the DHOase family, hydantoinase/dihydropyrimidinase subfamily. DPYS catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. It can catalyzes the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. DPYS is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.

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Keywords

DPYS Protein, Human, Recombinant (His & GST) DHPase dihydropyrimidinase DHP recombinant recombinant-proteins proteins protein

 

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