DPYS Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 56.8 kDa and the accession number is Q14117.
生物活性 | Testing in progress |
产品描述 | DPYS Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 56.8 kDa and the accession number is Q14117. |
种属 | Human |
表达系统 | Baculovirus-Insect Cells |
标签 | Tag Free |
蛋白编号 | Q14117 |
别名 | dihydropyrimidinase, DHPase, DHP |
蛋白构建 | A DNA sequence encoding the human DPYS (NP_001376.1) (Met1-Pro519) was fused with two additional amino acids (Gly&Pro) at the N-terminus. |
蛋白纯度 | > 95 % as determined by SDS-PAGE |
分子量 | 56.8 kDa (predicted) |
内毒素 | < 1.0 EU per μg of the protein as determined by the LAL method |
缓冲液 | Lyophilized from sterile 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 8.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | DPYS, also known as dihydropyrimidinase, belongs to the DHOase family, hydantoinase/dihydropyrimidinase subfamily. DPYS catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. It can catalyzes the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. DPYS is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria. |
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DPYS Protein, Human, Recombinant dihydropyrimidinase DHPase DHP recombinant recombinant-proteins proteins protein