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DHX33 Protein, Human, Recombinant (His)

DHX33 Protein, Human, Recombinant (His)

产品编号 TMPH-00980
别名: ATP-dependent RNA helicase DHX33, DEAH box protein 33, DDX33, DHX33

DHX33 Protein, Human, Recombinant (His) is expressed in E. coli.

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DHX33 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,800 20日内发货
100 μg ¥ 3,420 20日内发货
1 mg ¥ 14,600 20日内发货
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产品目录号及名称: DHX33 Protein, Human, Recombinant (His) (TMPH-00980)
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生物活性
技术参数
产品性质
产品描述 DHX33 Protein, Human, Recombinant (His) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-terminal 6xHis-tagged
蛋白编号 Q9H6R0
别名 ATP-dependent RNA helicase DHX33, DEAH box protein 33, DDX33, DHX33
氨基酸序列 MPEEAGFPPAKRFRPGSGPPSRAGSFPPGRQVVMLLTAGSGGRGGGGGRRQQPPLAQPSASPYPEAVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGIIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGAPVLYLEGRQHPIQVFYTKQPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSKTCRDIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFEKFDKMTVPEIQRCNLASVMLQLLAMK Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白构建 1-450 aa
蛋白纯度 > 85% as determined by SDS-PAGE.
分子量 53.7 kDa (predicted)
缓冲液 Tris-based buffer,50% glycerol
复溶方法 A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 Implicated in nucleolar organization, ribosome biogenesis, protein synthesis and cytoplasmic dsRNA sensing. Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. In the cytoplasm, promotes elongation-competent 80S ribosome assembly at the late stage of mRNA translation initiation. Senses cytosolic dsRNA mediating NLRP3 inflammasome formation in macrophages and type I interferon production in myeloid dendritic cells. Required for NLRP3 activation induced by viral dsRNA and bacterial RNA. In dendritic cells, required for induction of type I interferon production induced by cytoplasmic dsRNA via the activation of MAPK and NF-kappa-B signaling pathways.

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Keywords

DHX33 Protein, Human, Recombinant (His) ATP-dependent RNA helicase DHX33 DEAH box protein 33 DDX33 DHX33 recombinant recombinant-proteins proteins protein

 

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