DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 740 | 5日内发货 | ||
50 μg | ¥ 1,970 | 5日内发货 | ||
500 μg | ¥ 12,100 | 5日内发货 | ||
1 mg | ¥ 17,400 | 5日内发货 |
产品描述 | DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression. |
种属 | Human |
表达系统 | E. coli |
标签 | N-6His |
蛋白编号 | AAH07721.1 |
别名 | DNA Fragmentation Factor Subunit Alpha, DFF45, H13, ICAD, DFFA, DFF1, DNA Fragmentation Factor Subunit α, DNA Fragmentation Factor 45 kDa Subunit, DFF-45, Inhibitor of CAD |
氨基酸序列 | Met1-Thr331 |
蛋白构建 | Recombinant Human DNA Fragmentation Factor Subunit Alpha is produced by our E.coli expression system and the target gene encoding Met1-Thr331 is expressed with a 6His tag at the N-terminus. |
蛋白纯度 | Greater than 85% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 40-50 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. |
存储 |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
运输方式 |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
DFF45 Protein, Human, Recombinant (His) DNA Fragmentation Factor Subunit Alpha DFF45 H 13 DFF-1 H-13 H13 DFF 1 ICAD DFFA DFF1 DFF 45 DNA Fragmentation Factor Subunit α DNA Fragmentation Factor 45 kDa Subunit DFF-45 Inhibitor of CAD recombinant recombinant-proteins proteins protein