Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors; they are released by proteolytic cleavage of a signal sequence.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 820 | 5日内发货 | ||
50 μg | ¥ 2,480 | 5日内发货 | ||
500 μg | ¥ 12,100 | 5日内发货 | ||
1 mg | ¥ 17,400 | 5日内发货 |
产品描述 | Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors; they are released by proteolytic cleavage of a signal sequence. |
种属 | Human |
表达系统 | E. coli |
标签 | None |
蛋白编号 | Q8WTQ1 |
别名 | DEFB4, DEFB104B, hBD-4, DEFB104, BD-4, DEFB-4, Beta-Defensin 104, Beta-Defensin 4, β-Defensin 104, Defensin Beta 104, β-Defensin 4, Defensin β104, DEFB104A |
氨基酸序列 | Glu23-Pro72 |
蛋白构建 | Recombinant Human Beta-Defensin 4 is produced by our E.coli expression system and the target gene encoding Glu23-Pro72 is expressed. |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 9 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 130mM NaCl, pH 7.4. |
复溶方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
存储 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
运输方式 |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors; they are released by proteolytic cleavage of a signal sequence. |
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DEFB4 Protein, Human, Recombinant DEFB4 BD4 b-Defensin 4 DEFB104B hBD-4 DEFB104 DEFB 104 BD-4 DEFB-4 BD 4 Beta-Defensin 104 DEFB 4 Beta-Defensin 4 DEFB-104 β-Defensin 104 Defensin Beta 104 Defensin b 104 Defensin β 104 β-Defensin 4 Defensin β104 b-Defensin 104 DEFB104A recombinant recombinant-proteins proteins protein