CXCR3 Protein, Human, Recombinant (GST & His) is expressed in E. coli.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 1,800 | 20日内发货 | ||
100 μg | ¥ 3,420 | 20日内发货 | ||
1 mg | ¥ 14,600 | 20日内发货 |
产品描述 | CXCR3 Protein, Human, Recombinant (GST & His) is expressed in E. coli. |
种属 | Human |
表达系统 | E. coli |
标签 | N-terminal 6xHis-GST-tagged |
蛋白编号 | P49682 |
别名 | IP-10 receptor, CXCR3, CXC-R3, GPR9, Interferon-inducible protein 10 receptor, G protein-coupled receptor 9, CKR-L2, CD183, C-X-C chemokine receptor type 3, CXCR-3 |
氨基酸序列 | EVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLN Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. |
蛋白构建 | 4-50 aa |
蛋白纯度 | > 85% as determined by SDS-PAGE. |
分子量 | 36.6 kDa (predicted) |
缓冲液 | Tris-based buffer,50% glycerol |
复溶方法 | A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response.; Receptor for the C-X-C chemokine CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the proliferation, survival and angiogenic activity of human microvascular endothelial cells (HMVEC) through a cAMP-mediated signaling pathway. Does not promote cell chemotaxis respons. Interaction with CXCL4 or CXCL10 leads to activation of the p38MAPK pathway and contributes to inhibition of angiogenesis. Overexpression in renal cancer cells down-regulates expression of the anti-apoptotic protein HMOX1 and promotes apoptosis.; Mediates the activity of CXCL11. |
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CXCR3 Protein, Human, Recombinant (GST & His) IP-10 receptor CXCR3 CXC-R3 GPR9 Interferon-inducible protein 10 receptor G protein-coupled receptor 9 CKR-L2 CD183 C-X-C chemokine receptor type 3 CXCR-3 recombinant recombinant-proteins proteins protein