CTLA-4 Protein, Cynomolgus, Recombinant (hFc)

CTLA-4 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-60 KDa and the accession number is G7PL88.

规格	价格/CNY		数量
10 μg	￥ 380	5日内发货
50 μg	￥ 940	5日内发货
500 μg	￥ 5,810	5日内发货
1 mg	￥ 8,300	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 380

5日内发货

50 μg

￥ 940

5日内发货

500 μg

￥ 5,810

5日内发货

1 mg

￥ 8,300

5日内发货

产品描述	CTLA-4 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-60 KDa and the accession number is G7PL88.

种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	G7PL88
别名	Cytotoxic T-lymphocyte-associated antigen 4, Cytotoxic T-lymphocyte protein 4, CTLA4, CTLA-4, CD152
氨基酸序列	Ala37-Ser160
蛋白构建	Ala37-Ser160
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	45-60 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

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CTLA-4 Protein, Cynomolgus, Recombinant (hFc)

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