Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physiologic conditions. CTGF is pathologically viewed as a central mediator of tissue remodeling and fibrosis of various organs, including the lung, heart, liver, and kidney.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 550 | 5日内发货 | ||
50 μg | ¥ 1,670 | 5日内发货 | ||
500 μg | ¥ 13,700 | 5日内发货 | ||
1 mg | ¥ 20,500 | 5日内发货 |
产品描述 | Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physiologic conditions. CTGF is pathologically viewed as a central mediator of tissue remodeling and fibrosis of various organs, including the lung, heart, liver, and kidney. |
种属 | Human |
表达系统 | Human Cells |
标签 | C-6His |
蛋白编号 | Q5M8T4 |
别名 | CTGF, Connective tissue growth factor |
氨基酸序列 | Gln27-Ala349 |
蛋白构建 | Recombinant Human Connective Tissue Growth Factor is produced by our Mammalian expression system and the target gene encoding Gln27-Ala349 is expressed with a 6His tag at the C-terminus. |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 33-45 KDa, reducing conditions |
内毒素 | Less than 1 EU/µg as determined by LAL test. |
缓冲液 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 300mM NaCl, pH7.4. |
复溶方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
存储 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
运输方式 |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physiologic conditions. CTGF is pathologically viewed as a central mediator of tissue remodeling and fibrosis of various organs, including the lung, heart, liver, and kidney. |
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CTGF/CCN2 Protein, Human, Recombinant (HEK293, His) CTGF Connective tissue growth factor recombinant recombinant-proteins proteins protein