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CORIN Protein, Human, Recombinant (His)

CORIN Protein, Human, Recombinant (His)

产品编号 TMPH-00986
别名: TMPRSS10, Pro-ANP-converting enzyme, Heart-specific serine proteinase ATC2, Transmembrane protease serine 10, Corin, CRN, CORIN, Atrial natriuretic peptide-converting enzyme

CORIN Protein, Human, Recombinant (His) is expressed in E. coli.

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CORIN Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,510 20日内发货
100 μg ¥ 2,840 20日内发货
1 mg ¥ 12,200 20日内发货
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产品目录号及名称: CORIN Protein, Human, Recombinant (His) (TMPH-00986)
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生物活性
技术参数
产品性质
产品描述 CORIN Protein, Human, Recombinant (His) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-terminal 6xHis-tagged
蛋白编号 Q9Y5Q5
别名 TMPRSS10, Pro-ANP-converting enzyme, Heart-specific serine proteinase ATC2, Transmembrane protease serine 10, Corin, CRN, CORIN, Atrial natriuretic peptide-converting enzyme
氨基酸序列 MKQSPALAPEERCRRAGSPKPVLRADDNNMGNGCSQKLATANLLRFLLLVLIPCICALVLLLVILLSYVGTLQKVYFKSNGSEPLVTDGEIQGSDVILTNTIYNQSTVVS Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白构建 1-110 aa
蛋白纯度 > 85% as determined by SDS-PAGE.
分子量 16.0 kDa (predicted)
缓冲液 If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶方法 A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 Serine-type endopeptidase involved in atrial natriuretic peptide (NPPA) and brain natriuretic peptide (NPPB) processing. Converts through proteolytic cleavage the non-functional propeptides NPPA and NPPB into their active hormones, ANP and BNP(1-32) respectively, thereby regulating blood pressure in the heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney.; has weaker endopeptidase activity compared to isoform 1.

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Keywords

CORIN Protein, Human, Recombinant (His) TMPRSS10 Pro-ANP-converting enzyme Heart-specific serine proteinase ATC2 Transmembrane protease serine 10 Corin CRN CORIN Atrial natriuretic peptide-converting enzyme recombinant recombinant-proteins proteins protein

 

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