Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 1,320 | 20日内发货 | ||
100 μg | ¥ 2,470 | 20日内发货 | ||
1 mg | ¥ 10,700 | 20日内发货 |
产品描述 | Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. |
种属 | Human |
表达系统 | E. coli |
标签 | N-terminal 6xHis-SUMO-tagged |
蛋白编号 | P0C0L5 |
别名 | C4B, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, Basic complement C4, Complement C4-B, CPAMD3, CO4 |
氨基酸序列 | EAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGCQV Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. |
蛋白构建 | 1454-1744 aa |
蛋白纯度 | > 90% as determined by SDS-PAGE. |
分子量 | 49.1 kDa (predicted) |
缓冲液 | Tris-based buffer,50% glycerol |
复溶方法 | A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.; Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
Complement C4-B Protein, Human, Recombinant (His & SUMO) C4B C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 Basic complement C4 Complement C4-B CPAMD3 CO4 recombinant recombinant-proteins proteins protein