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Complement C4-B Protein, Human, Recombinant (His & SUMO)

Complement C4-B Protein, Human, Recombinant (His & SUMO)

产品编号 TMPH-01131
别名: C4B, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, Basic complement C4, Complement C4-B, CPAMD3, CO4

Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

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Complement C4-B Protein, Human, Recombinant (His & SUMO)
规格 价格/CNY 货期 数量
20 μg ¥ 1,320 20日内发货
100 μg ¥ 2,470 20日内发货
1 mg ¥ 10,700 20日内发货
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产品目录号及名称: Complement C4-B Protein, Human, Recombinant (His & SUMO) (TMPH-01131)
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生物活性
技术参数
产品性质
产品描述 Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-terminal 6xHis-SUMO-tagged
蛋白编号 P0C0L5
别名 C4B, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, Basic complement C4, Complement C4-B, CPAMD3, CO4
氨基酸序列 EAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGCQV Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白构建 1454-1744 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 49.1 kDa (predicted)
缓冲液 Tris-based buffer,50% glycerol
复溶方法 A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.; Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

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Keywords

Complement C4-B Protein, Human, Recombinant (His & SUMO) C4B C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 Basic complement C4 Complement C4-B CPAMD3 CO4 recombinant recombinant-proteins proteins protein

 

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